Here are some window configuration files to get your started.
There are comments at the top of each file that describe what
they make VM do.

Pick one of these files and copy it somewhere, like say
~/.vm.windows.  Then put

(setq vm-window-configuration-file "~/.vm.windows")

in your .vm file.

VM's window configuration system works by assigning
configurations to actions.  Nearly every VM command can have its
own separate configuration.  However, there are also
configurations for classes of actions, like 'startup' and
'composing-message'.  These configuration classes cover all the
commands that fit into the class.  For example, all the commands
that send out mail fall under the 'composing-message' config.

If there is no command specific configuration, the class
configuration for that command is used.  If there is no class
configuration, then the 'default' configuration is used.  If
there is no 'default' configuration, VM does <something> to get
its buffers displayed, and <something> is undefined.  If you
don't set up a window configuration VM might start displaying your
folders by skywriting or some such.  So, for your privacy's sake,
you should set up window configurations. :)

To set a configuration, you should use normal Emacs window and
buffer selection and sizing commands to make the screen look like
you want it to look for a particular action.  Then run
vm-save-window-configuration.  This is bound to W S in vm-mode
buffers, and C-c C-v W S in VM mail-mode and edit-message buffers.
You can of course use M-x vm-save-window-configuration from any
other buffer.  You will be asked for a configuration name, and
there is completion for the names.  If a configuration for the
name you select already exists, it will be overwritten.

To delete a configuration, use vm-delete-window-configuration,
bound to W D in vm-mode buffer.  The action that you specify will
no longer have a configuration associated with it.

vm-apply-window-configuration (W W) makes the screen look like a
particular configuration.  You might use this as an aid to
setting up configurations based on some common framework.  W W is
an easy way to call up a config instead of recreating it each
time.